General Information
-
DRAMP ID
- DRAMP01800
-
Peptide Name
- Temporin-1PRb (Temporin 1PRb; Frogs, amphibians, animals)
-
Source
- Rana pirica (Hokkaido frog)
-
Family
- Belongs to the frog skin active peptide family (Brevinin subfamily)
-
Gene
- Not found
-
Sequence
- ILPILGNLLNSLL
-
Sequence Length
- 13
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
-
Target Organism
-
- Gram-negative bacterium: Escherichia coli;
- Gram-positive bacterium: Staphylococcus aureus.
- Yeast: Candida albicans (MIC>100 µM).
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP01800.
Physicochemical Information
-
Formula
- C66H117N15O17
Absent Amino Acids
- ACDEFHKMQRTVWY
Common Amino Acids
- L
Mass
- 1392.74
PI
- 5.52
Basic Residues
- 0
Acidic Residues
- 0
Hydrophobic Residues
- 8
Net Charge
- 0
-
Boman Index
- 23.62
Hydrophobicity
- 1.692
Aliphatic Index
- 240
Half Life
-
- Mammalian:20 hour
- Yeast:30 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 4
DRAMP01800
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
-
Title
- A family of brevinin-2 peptides with potent activity against Pseudomonas aeruginosa from the skin of the Hokkaido frog, Rana pirica.
-
Pubmed ID
- 15003829
-
Reference
- Regul. Pept 2004; 118: 135-141.
-
Author
- Conlon JM et al Pal T.