• DRAMP ID

    • DRAMP01801
    • Peptide Name

    • Temporin-1DYa (Frogs, amphibians, animals)
    • Source

    • Rana dybowskii (Dybovsky's frog) (Korean brown frog)
    • Family

    • Belongs to the frog skin active peptide family (Brevinin subfamily)
    • Gene

    • Not found
    • Sequence

    • FIGPIISALASLFG
    • Sequence Length

    • 14
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
    • Target Organism

      • Gram-positive bacterium: Staphylococcus aureus (MIC>60 µM);
      • Gram-negative bacterium: Escherichia coli (MIC>60 µM).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP01801 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP01801.
    • Formula

    • C69H108N14O17
    • Absent Amino Acids

    • CDEHKMNQRTVWY
    • Common Amino Acids

    • I
    • Mass

    • 1405.7
    • PI

    • 5.52
    • Basic Residues

    • 0
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 9
    • Net Charge

    • 0
    • Boman Index

    • 29.26
    • Hydrophobicity

    • 1.879
    • Aliphatic Index

    • 153.57
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 4

DRAMP01801

    • Function

    • Active against the Gram-positive bacteria
  • ·Literature 1
    • Title

    • Cytolytic peptides belonging to the brevinin-1 and brevinin-2 families isolated from the skin of the Japanese brown frog, Rana dybowskii.
    • Reference

    • Toxicon. 2007 Nov;50(6):746-756.
    • Author

    • Conlon JM, Kolodziejek J, Nowotny N, Leprince J, Vaudry H, Coquet L, Jouenne T, Iwamuro S.