General Information

    • DRAMP ID

    • DRAMP01837

    • Peptide Name

    • Ascaphin-4M (Frogs, amphibians, animals)

    • Source

    • A. montanus (North America inland frog)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GFKDWIKGAAKKLIKTVASNIANQ

    • Sequence Length

    • 24

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01837 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01837.

Physicochemical Information

    • Formula

    • C119H197N33O32

    • Absent Amino Acids

    • CEHMPRY

    • Common Amino Acids

    • K

    • Mass

    • 2602.07

    • PI

    • 10.18

    • Basic Residues

    • 5

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 11

    • Net Charge

    • +4

    • Boman Index

    • -23.11

    • Hydrophobicity

    • -0.217

    • Aliphatic Index

    • 93.75

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 239.13

    • Polar Residues

    • 6

DRAMP01837

DRAMP01837 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Antimicrobial peptides from the skins of North American frogs.

    • Reference

    • Biochim Biophys Acta. 2009 Aug;1788(8):1556-1563.

    • Author

    • Conlon JM, Kolodziejek J, Nowotny N.