• DRAMP ID

    • DRAMP01871
    • Peptide Name

    • Brevinin-1SPc (Frogs, amphibians, animals)
    • Source

    • Rana septentrionalis (mink frog)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • FLPIIASVAAKLIPSIVCRITKKC
    • Sequence Length

    • 24
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • [Ref.15556063]HC50=3 µM against human erythrocytes
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP01871 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP01871.
    • Formula

    • C120H210N30O28S2
    • Absent Amino Acids

    • DEGHMNQWY
    • Common Amino Acids

    • I
    • Mass

    • 2585.29
    • PI

    • 9.85
    • Basic Residues

    • 4
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 13
    • Net Charge

    • +4
    • Boman Index

    • 12.55
    • Hydrophobicity

    • 1.25
    • Aliphatic Index

    • 150.42
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 125
    • Absorbance 280nm

    • 5.43
    • Polar Residues

    • 5

DRAMP01871

DRAMP01871 chydropathy plot
    • Function

    • Has inhibitory activity towards reference strains of bacteria and an opportunistic yeast pathogen. Also has hemolytic activity against human erythrocytes.
  • ·Literature 1
    • Title

    • Purification and characterization of antimicrobial peptides from the skin secretions of the mink frog (Rana septentrionalis).
    • Reference

    • Comp Biochem Physiol C Toxicol Pharmacol. 2004 Oct;139(1-3):31-38.
    • Author

    • Bevier CR, Sonnevend A, Kolodziejek J, Nowotny N, Nielsen PF, Conlon JM.