General Information

    • DRAMP ID

    • DRAMP01889

    • Peptide Name

    • Brevinin-1TOa (Frogs, amphibians, animals)

    • Source

    • Rana tagoi okiensis

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GIGSILGVIAKGLPTLISWIKNR

    • Sequence Length

    • 23

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal

    • Target Organism

      • Gram-negative bacterium: E. coli (MIC=20 µM);
      • Gram-positive bacterium: S. aureus (MIC=5 µM).
      • Yeast: C. albicans (MIC=20 µM).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01889 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01889.

Physicochemical Information

    • Formula

    • C112H192N30O28

    • Absent Amino Acids

    • CDEFHMQY

    • Common Amino Acids

    • I

    • Mass

    • 2406.94

    • PI

    • 11.17

    • Basic Residues

    • 3

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 11

    • Net Charge

    • +3

    • Boman Index

    • 9.27

    • Hydrophobicity

    • 0.77

    • Aliphatic Index

    • 152.61

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 250

    • Polar Residues

    • 8

DRAMP01889

DRAMP01889 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Evidence from the primary structures of dermal antimicrobial peptides that Rana tagoi okiensis and Rana tagoi tagoi (Ranidae) are not conspecific subspecies.

    • Reference

    • Toxicon. 2010 Feb-Mar;55(2-3):430-435.

    • Author

    • Conlon JM, Coquet L, Jouenne T, Leprince J, Vaudry H, Iwamuro S.