General Information
-
DRAMP ID
- DRAMP01896
-
Peptide Name
- Brevinin-1CG1 (Frogs, amphibians, animals)
-
Source
- Amolops chunganensis (Chungan torrent frog)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- FLSTALKVAANVVPTLFCKITKKC
-
Sequence Length
- 24
-
UniProt Entry
- No entry found
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
-
Target Organism
-
- Gram-positive bacteria: Rhodococcus rhodochrous X15 (MIC=9 µM), Bacillus licheniformis X39 (IS) (MIC=75 µM);
- Gram-negative bacterium: Escherichia coli (ATCC 25922) (MIC=150 µM).
- Fungi: Slime mold 090223 (IS) (MIC=75 µM).
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP01896.
Physicochemical Information
-
Formula
- C120H203N29O30S2
Absent Amino Acids
- DEGHMQRWY
Common Amino Acids
- K
Mass
- 2596.23
PI
- 9.7
Basic Residues
- 4
Acidic Residues
- 0
Hydrophobic Residues
- 12
Net Charge
- +4
-
Boman Index
- 5.8
Hydrophobicity
- 0.871
Aliphatic Index
- 113.75
Half Life
-
- Mammalian:1.1 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 125
Absorbance 280nm
- 5.43
Polar Residues
- 7
DRAMP01896
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
-
Title
- Characterization of diverse antimicrobial peptides in skin secretions of Chungan torrent frog Amolops chunganensis.
-
Pubmed ID
- 22951323
-
Reference
- Peptides. 2012 Nov;38(1):41-53.
-
Author
- Yang X, Xia J, Yu Z, Hu Y, Li F, Meng H, Yang S, Liu J, Wang H.