General Information

    • DRAMP ID

    • DRAMP01901

    • Peptide Name

    • Brevinin-2CG1 (Frogs, amphibians, animals)

    • Source

    • Amolops chunganensis

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GILDKLKEFGISAARGVAQSLLNTASCKLAKTC

    • Sequence Length

    • 33

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram-, Antifungal

    • Target Organism

      • Gram-negative bacteria: P. faecalis X29, S. rubidaea.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01901 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01901.

Physicochemical Information

    • Formula

    • C148H256N42O45S2

    • Absent Amino Acids

    • HMPWY

    • Common Amino Acids

    • AL

    • Mass

    • 3408.03

    • PI

    • 9.31

    • Basic Residues

    • 5

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 14

    • Net Charge

    • +3

    • Boman Index

    • -24.28

    • Hydrophobicity

    • 0.3

    • Aliphatic Index

    • 106.67

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 125

    • Absorbance 280nm

    • 3.91

    • Polar Residues

    • 11

DRAMP01901

DRAMP01901 chydropathy plot

Comments Information

    • Function

    • Primarily active against Gram-positive bacteria. Also highly active against Gram-negative P. faecalis X29 and S. rubidaea.

Literature Information

  • ·Literature 1

    • Title

    • Characterization of diverse antimicrobial peptides in skin secretions of Chungan torrent frog Amolops chunganensis.

    • Reference

    • Peptides. 2012 Nov;38(1):41-53.

    • Author

    • Yang X, Xia J, Yu Z, Hu Y, Li F, Meng H, Yang S, Liu J, Wang H.