General Information

    • DRAMP ID

    • DRAMP01916

    • Peptide Name

    • Brevinin-2GU (Frogs, amphibians, animals)

    • Source

    • Hylarana guntheri (Asian frog)

    • Family

    • Belongs to the frog skin active peptide family (Brevinin subfamily)

    • Gene

    • Not found

    • Sequence

    • GVIIDTLKGAAKTVAAELLRKAHCKLTNSC

    • Sequence Length

    • 30

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01916 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01916.

Physicochemical Information

    • Formula

    • C135H238N40O40S2

    • Absent Amino Acids

    • FMPQWY

    • Common Amino Acids

    • A

    • Mass

    • 3125.74

    • PI

    • 9.31

    • Basic Residues

    • 6

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 13

    • Net Charge

    • +4

    • Boman Index

    • -23.97

    • Hydrophobicity

    • 0.303

    • Aliphatic Index

    • 114

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 125

    • Absorbance 280nm

    • 4.31

    • Polar Residues

    • 9

DRAMP01916

DRAMP01916 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Cloning and expression of a novel insulin-releasing peptide, brevinin-2GU from Escherichia coli.

    • Reference

    • J Biosci Bioeng. 2009 Apr;107(4):460-463.

    • Author

    • Zhou QF, Li MY, Li CW.