General Information
-
DRAMP ID
- DRAMP01988
-
Peptide Name
- Brevinin-1LTa (Frogs, amphibians, animals)
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Source
- Hylarana latouchii (Chinese frog fauna)
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Family
- Belongs to the frog skin active peptide family (Brevinin subfamily)
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Gene
- Not found
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Sequence
- FFGTALKIAANVLPTAICKILKKC
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Sequence Length
- 24
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UniProt Entry
- No entry found
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Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Antifungal
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Cell membrance
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
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Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP01988.
Physicochemical Information
-
Formula
- C120H203N29O28S2
Absent Amino Acids
- DEHMQRSWY
Common Amino Acids
- AK
Mass
- 2564.23
PI
- 9.7
Basic Residues
- 4
Acidic Residues
- 0
Hydrophobic Residues
- 13
Net Charge
- +4
-
Boman Index
- 16.28
Hydrophobicity
- 1.017
Aliphatic Index
- 126.25
Half Life
-
- Mammalian:1.1 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 125
Absorbance 280nm
- 5.43
Polar Residues
- 6
DRAMP01988
Comments Information
Tissue specificity
- Expressed by the skin glands.
Literature Information
- ·Literature 1
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Title
- The novel antimicrobial peptides from skin of Chinese broad-folded frog, Hylarana latouchii (Anura:Ranidae).
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Pubmed ID
- 19022312
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Reference
- Peptides. 2009 Feb;30(2):273-282.
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Author
- Wang H, Lu Y, Zhang X, Hu Y, Yu H, Liu J, Sun J.