• DRAMP ID

    • DRAMP01989
    • Peptide Name

    • Brevinin-1LTb (Frogs, amphibians, animals)
    • Source

    • Hylarana latouchii (Chinese frog fauna)
    • Family

    • Belongs to the frog skin active peptide family (Brevinin subfamily)
    • Gene

    • Not found
    • Sequence

    • FFGTALKIAANILPTAICKILKKC
    • Sequence Length

    • 24
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Cell membrance
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP01989 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP01989.
    • Formula

    • C121H205N29O28S2
    • Absent Amino Acids

    • DEHMQRSVWY
    • Common Amino Acids

    • AIK
    • Mass

    • 2578.26
    • PI

    • 9.7
    • Basic Residues

    • 4
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 13
    • Net Charge

    • +4
    • Boman Index

    • 17.16
    • Hydrophobicity

    • 1.029
    • Aliphatic Index

    • 130.42
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 125
    • Absorbance 280nm

    • 5.43
    • Polar Residues

    • 6

DRAMP01989

DRAMP01989 chydropathy plot
    • This peptide differs from Brevinin-1LTa by only one residue (I vs. V). This conservative change allows to predict that this peptide has all the activities of Brevinin-1LTa.

    • Tissue specificity

    • Expressed by the skin glands.
  • ·Literature 1
    • Title

    • The novel antimicrobial peptides from skin of Chinese broad-folded frog, Hylarana latouchii (Anura:Ranidae).
    • Reference

    • Peptides. 2009 Feb;30(2):273-282.
    • Author

    • Wang H, Lu Y, Zhang X, Hu Y, Yu H, Liu J, Sun J.