• DRAMP ID

    • DRAMP02011
    • Peptide Name

    • Brevinin-2Tb (Frogs, amphibians, animals)
    • Source

    • Rana temporaria (European common frog)
    • Family

    • Belongs to the frog skin active peptide family (Brevinin subfamily)
    • Gene

    • Not found
    • Sequence

    • GILDTLKHLAKTAGKGALQSLLNHASCKLSGQC
    • Sequence Length

    • 33
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP02011 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP02011.
    • Formula

    • C145H250N44O44S2
    • Absent Amino Acids

    • EFMPRVWY
    • Common Amino Acids

    • L
    • Mass

    • 3377.97
    • PI

    • 9.31
    • Basic Residues

    • 6
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 12
    • Net Charge

    • +5
    • Boman Index

    • -20.38
    • Hydrophobicity

    • 0.058
    • Aliphatic Index

    • 106.67
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 125
    • Absorbance 280nm

    • 3.91
    • Polar Residues

    • 12

DRAMP02011

DRAMP02011 chydropathy plot
    • Function

    • Antimicrobial peptide.(By similarity)
    • Tissue specificity

    • Expressed by the skin glands.
    • PTM

    • Problely contains one disulfide bond 27-33.
  • ·Literature 1
    • Title

    • Antimicrobial peptides from amphibian skin: what do they tell us?
    • Reference

    • Biopolymers. 1998;47(6):435-450.
    • Author

    • Simmaco M, Mignogna G, Barra D.