• DRAMP ID

    • DRAMP02015
    • Peptide Name

    • Brevinin-2Td (Frogs, amphibians, animals)
    • Source

    • Rana temporaria (European common frog)
    • Family

    • Belongs to the frog skin active peptide family (Brevinin subfamily)
    • Gene

    • Not found
    • Sequence

    • GLWETIKNFGKKFTLNILHNLKCKIGGGC
    • Sequence Length

    • 29
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Cell membrane
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP02015 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP02015.
    • Formula

    • C148H238N40O37S2
    • Absent Amino Acids

    • ADMPQRSVY
    • Common Amino Acids

    • GK
    • Mass

    • 3233.88
    • PI

    • 9.6
    • Basic Residues

    • 6
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 10
    • Net Charge

    • +5
    • Boman Index

    • -14.29
    • Hydrophobicity

    • -0.059
    • Aliphatic Index

    • 94.14
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 5625
    • Absorbance 280nm

    • 200.89
    • Polar Residues

    • 12

DRAMP02015

DRAMP02015 chydropathy plot
    • Function

    • Antibacterial activity against representative Gram-negative and Gram-positive bacteria.
  • ·Literature 1
    • Title

    • Antimicrobial peptides from amphibian skin: what do they tell us?
    • Reference

    • Biopolymers. 1998;47(6):435-450.
    • Author

    • Simmaco M, Mignogna G, Barra D.