General Information

    • DRAMP ID

    • DRAMP02140

    • Peptide Name

    • XPF-SP1 (Frogs, amphibians, animals)

    • Source

    • Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GFWSSALEGLKKFAKGGLEALTNPK

    • Sequence Length

    • 25

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02140 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02140.

Physicochemical Information

    • Formula

    • C123H193N31O34

    • Absent Amino Acids

    • CDHIMQRVY

    • Common Amino Acids

    • GKL

    • Mass

    • 2650.07

    • PI

    • 9.53

    • Basic Residues

    • 4

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 10

    • Net Charge

    • +2

    • Boman Index

    • -14.67

    • Hydrophobicity

    • -0.252

    • Aliphatic Index

    • 74.4

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 229.17

    • Polar Residues

    • 8

DRAMP02140

DRAMP02140 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Genome duplications within the Xenopodinae do not increase the multiplicity of antimicrobial peptides in Silurana paratropicalis and Xenopus andrei skin secretions.

    • Reference

    • Comp Biochem Physiol Part D Genomics Proteomics. 2011 Jun;6(2):206-212.

    • Author

    • Mechkarska M, Eman A, Coquet L, Jérôme L, Jouenne T, Vaudry H, King JD, Takada K, Conlon JM.