General Information

    • DRAMP ID

    • DRAMP02142

    • Peptide Name

    • CPF-SP1 (Frogs, amphibians, animals)

    • Source

    • Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GFLGPLLKLGLKGVAKVLPHLIPSRQQ

    • Sequence Length

    • 27

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • Acinetobacter baumannii (MIC=12,5; Klebsiella pneumoniae=25

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02142 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02142.

Physicochemical Information

    • Formula

    • C136H231N37O31

    • Absent Amino Acids

    • CDEMNTWY

    • Common Amino Acids

    • L

    • Mass

    • 2880.56

    • PI

    • 11.26

    • Basic Residues

    • 5

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 12

    • Net Charge

    • +5

    • Boman Index

    • 5.28

    • Hydrophobicity

    • 0.389

    • Aliphatic Index

    • 140.74

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 5

DRAMP02142

DRAMP02142 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Genome duplications within the Xenopodinae do not increase the multiplicity of antimicrobial peptides in Silurana paratropicalis and Xenopus andrei skin secretions.

    • Reference

    • Comp Biochem Physiol Part D Genomics Proteomics. 2011 Jun;6(2):206-212.

    • Author

    • Mechkarska M, Eman A, Coquet L, Jérôme L, Jouenne T, Vaudry H, King JD, Takada K, Conlon JM.