General Information

    • DRAMP ID

    • DRAMP02159

    • Peptide Name

    • Melittin-related peptide (Frogs, amphibians, animals)

    • Source

    • Rana arvalis (Moor frog)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • FVGAALKVLANVLPPVISWIKQ

    • Sequence Length

    • 22

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Unknown

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02159 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02159.

Physicochemical Information

    • Formula

    • C115H187N27O26

    • Absent Amino Acids

    • CDEHMRTY

    • Common Amino Acids

    • V

    • Mass

    • 2363.92

    • PI

    • 10

    • Basic Residues

    • 2

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 14

    • Net Charge

    • +2

    • Boman Index

    • 25.76

    • Hydrophobicity

    • 1.15

    • Aliphatic Index

    • 155

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 261.9

    • Polar Residues

    • 3

DRAMP02159

DRAMP02159 chydropathy plot

Comments Information

    • Function

    • Amphibian defensive peptide.

    • Tissue specificity

    • Expressed by the skin glands.

Literature Information

  • ·Literature 1

    • Title

    • Mass spectrometric study of peptides secreted by the skin glands of the brown frog Rana arvalis from the Moscow region.

    • Reference

    • Rapid Commun Mass Spectrom. 2009 May;23(9):1241-1248.

    • Author

    • Samgina TY, Artemenko KA, Gorshkov VA, Ogourtsov SV, Zubarev RA, Lebedev AT.