General Information

    • DRAMP ID

    • DRAMP02162

    • Peptide Name

    • Peroniin-1.3a (Frogs, amphibians, animals)

    • Source

    • Litoria peronii (Emerald spotted tree frog) (Hyla peronii)

    • Family

    • Belongs to the frog skin active peptide family (Peroniin subfamily)

    • Gene

    • Not found

    • Sequence

    • DAQEKRQPWLPFV

    • Sequence Length

    • 13

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Unknown

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02162 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02162.

Physicochemical Information

    • Formula

    • C75H112N20O20

    • Absent Amino Acids

    • CGHIMNSTY

    • Common Amino Acids

    • PQ

    • Mass

    • 1613.84

    • PI

    • 6.07

    • Basic Residues

    • 2

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 5

    • Net Charge

    • 0

    • Boman Index

    • -31

    • Hydrophobicity

    • -1.069

    • Aliphatic Index

    • 60

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 458.33

    • Polar Residues

    • 0

DRAMP02162

Comments Information

    • Function

    • Amphibian defensive peptide.

    • Tissue specificity

    • Expressed by the skin dorsal glands.

Literature Information

  • ·Literature 1

    • Title

    • The host-defence skin peptide profiles of Peron's Tree Frog Litoria peronii in winter and summer. Sequence determination by electrospray mass spectrometry and activities of the peptides.

    • Reference

    • Rapid Commun Mass Spectrom. 2009 Sep;23(17):2628-2636.

    • Author

    • Bilusich D, Jackway RJ, Musgrave IF, Tyler MJ, Bowie JH.