General Information

    • DRAMP ID

    • DRAMP02164

    • Peptide Name

    • Ranatensin (Frogs, amphibians, animals)

    • Source

    • Rana pipiens (Northern leopard frog)

    • Family

    • Belongs to the bombesin/neuromedin-B/ranatensin family

    • Gene

    • Not found

    • Sequence

    • QVPQWAVGHFM

    • Sequence Length

    • 11

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Unknown

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02164 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02164.

Physicochemical Information

    • Formula

    • C61H86N16O14S

    • Absent Amino Acids

    • CDEIKLNRSTY

    • Common Amino Acids

    • QV

    • Mass

    • 1299.51

    • PI

    • 6.74

    • Basic Residues

    • 1

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 5

    • Net Charge

    • +1

    • Boman Index

    • 2.75

    • Hydrophobicity

    • 0.164

    • Aliphatic Index

    • 61.82

    • Half Life

      • Mammalian:0.8 hour
      • Yeast:10 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 550

    • Polar Residues

    • 1

DRAMP02164

Comments Information

    • Function

    • Amphibian defensive peptide.

    • Tissue specificity

    • Expressed by the skin glands.

Literature Information

  • ·Literature 1

    • Title

    • Molecular cloning of cDNAs encoding the human bombesin-like peptide neuromedin B. Chromosomal localization and comparison to cDNAs encoding its amphibian homolog ranatensin.

    • Reference

    • J Biol Chem. 1988 Sep 15;263(26):13317-23.

    • Author

    • Krane IM, Naylor SL, Helin-Davis D, Chin WW, Spindel ER.