General Information

    • DRAMP ID

    • DRAMP02227

    • Peptide Name

    • Ranatuerin-2Pa (Frogs, amphibians, animals)

    • Source

    • Rana pipiens (Northern leopard frog)

    • Family

    • Belongs to the frog skin active peptide family (Brevinin subfamily)

    • Gene

    • Not found

    • Sequence

    • GFLSTVKNLATNVAGTVIDTIKCKVTGGC

    • Sequence Length

    • 29

    • Protein Existence

    • Transcript level

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02227 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02227.

Physicochemical Information

    • Formula

    • C126H216N34O40S2

    • Absent Amino Acids

    • EHMPQRWY

    • Common Amino Acids

    • T

    • Mass

    • 2911.42

    • PI

    • 8.86

    • Basic Residues

    • 3

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 11

    • Net Charge

    • +2

    • Boman Index

    • -6.14

    • Hydrophobicity

    • 0.576

    • Aliphatic Index

    • 100.69

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 125

    • Absorbance 280nm

    • 4.46

    • Polar Residues

    • 14

DRAMP02227

DRAMP02227 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Granular gland transcriptomes in stimulated amphibian skin secretions.

    • Reference

    • Biochem J. 2003 Apr 1;371(Pt 1):125-130.

    • Author

    • Chen T, Farragher S, Bjourson AJ, Orr DF, Rao P, Shaw C.