• DRAMP ID

    • DRAMP02233
    • Peptide Name

    • Ranatuerin-6 (Frogs, amphibians, animals)
    • Source

    • Lithobates catesbeiana (American bullfrog) (Rana catesbeiana)
    • Family

    • Belongs to the frog skin active peptide family (Brevinin subfamily)
    • Gene

    • Unknow
    • Sequence

    • FISAIASMLGKFL
    • Sequence Length

    • 13
    • Evidence code

    • Protein level
    • Biological Activity

    • Antibacterial, Antiviral
    • Target Organism

      • Gram-positive bacterium: Staphylococcus aureus (MIC=100 ┬ÁM).
    • Hemolytic activity

    • Unknown
    • Binding Traget

    • Unknow
    • Structure

    • Unknow
    • Structure Description

    • Unknow
    • PDB ID

    • Unknow
    • DRAMP02233 helical wheel diagram
    • Formula

    • C67H108N14O16S
    • Absent Amino Acids

    • CDEHNPQRTVWY
    • Common Amino Acids

    • AFILS
    • Mass

    • 1611.97
    • PI

    • 9.7
    • Basic Residues

    • 1
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 8
    • Boman Index

    • 20.2
    • Hydrophobicity

    • 167.69
    • Aliphatic Index

    • 135.38
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 3

DRAMP02233

    • This peptide could inhibit HIV infection <10% at a concentration that is also toxic to T cells (J Virol 2005; 79

    • 11598-11606).
  • Literature 1
    • Reference

    • Biochem Biophys Res Commun. 1998 Sep 29;250(3):589-592.
    • Author

    • Goraya J, Knoop FC, Conlon JM.
    • Title

    • Ranatuerins: antimicrobial peptides isolated from the skin of the American bullfrog, Rana catesbeiana.