• DRAMP ID

    • DRAMP02234
    • Peptide Name

    • Ranatuerin-7 (Frogs, amphibians, animals)
    • Source

    • Lithobates catesbeiana (American bullfrog) (Rana catesbeiana)
    • Family

    • Belongs to the frog skin active peptide family (Brevinin subfamily)
    • Gene

    • Not found
    • Sequence

    • FLSAIASMLGKFL
    • Sequence Length

    • 13
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+
    • Target Organism

      • Gram-positive bacterium: Staphylococcus aureus (MIC=200 µM).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP02234 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP02234.
    • Formula

    • C67H108N14O16S
    • Absent Amino Acids

    • CDEHNPQRTVWY
    • Common Amino Acids

    • L
    • Mass

    • 1397.74
    • PI

    • 8.75
    • Basic Residues

    • 1
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 8
    • Net Charge

    • +1
    • Boman Index

    • 20.2
    • Hydrophobicity

    • 1.623
    • Aliphatic Index

    • 135.38
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 3

DRAMP02234

    • Function

    • Antibacterial activity against Gram-positive bacterium S. aureus.
    • Tissue specificity

    • Expressed by the skin glands.
  • ·Literature 1
    • Title

    • Ranatuerins: antimicrobial peptides isolated from the skin of the American bullfrog, Rana catesbeiana.
    • Reference

    • Biochem Biophys Res Commun. 1998 Sep 29;250(3):589-592.
    • Author

    • Goraya J, Knoop FC, Conlon JM.