• DRAMP ID

    • DRAMP02243
    • Peptide Name

    • Ranatuerin-1T (Brevinin-2T; Frogs, amphibians, animals)
    • Source

    • Rana temporaria (European common frog)
    • Family

    • Belongs to the frog skin active peptide family (Brevinin subfamily)
    • Gene

    • Not found
    • Sequence

    • GLLSGLKKVGKHVAKNVAVSLMDSLKCKISGDC
    • Sequence Length

    • 33
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
    • Target Organism

      • Gram-negative bacterium: Escherichia coli;
      • Gram-positive bacterium: Staphylococcus aureus.
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP02243 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP02243.
    • Formula

    • C147H260N42O43S3
    • Absent Amino Acids

    • EFPQRTWY
    • Common Amino Acids

    • K
    • Mass

    • 3400.12
    • PI

    • 9.51
    • Basic Residues

    • 7
    • Acidic Residues

    • 2
    • Hydrophobic Residues

    • 12
    • Net Charge

    • +5
    • Boman Index

    • -17.67
    • Hydrophobicity

    • 0.27
    • Aliphatic Index

    • 112.12
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 125
    • Absorbance 280nm

    • 3.91
    • Polar Residues

    • 11

DRAMP02243

DRAMP02243 chydropathy plot
    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • Ranatuerin 1T: an antimicrobial peptide isolated from the skin of the frog, Rana temporaria.
    • Reference

    • Peptides. 1999;20(2):159-163.
    • Author

    • Goraya J, Knoop FC, Conlon JM.
  • ·Literature 2
    • Title

    • Antimicrobial peptides from amphibian skin: what do they tell us?
    • Reference

    • Biopolymers. 1998;47(6):435-450.
    • Author

    • Simmaco M, Mignogna G, Barra D.