• DRAMP ID

    • DRAMP02318
    • Peptide Name

    • Grammistin Pp1 (Group II grammistin; fish, chordates, animals)
    • Source

    • Pogonoperca punctata (Clown grouper) (Bearded grouper)
    • Family

    • Belongs to the grammistin family (Group 2 subfamily)
    • Gene

    • Not found
    • Sequence

    • FIGGIISFFKRLF
    • Sequence Length

    • 13
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
    • Target Organism

      • Gram-positive bacteria: Bacillus subtilis IAM 1026 (MIC=3.13 µg/ml), Staphylococcus aureus IAM 1011 (MIC=3.13 µg/ml);
      • Gram-negative bacteria: Aeromonas salmonicida NCIBM 1102 (MIC=50 µg/ml), Escherichia coli JCM 1649 (MIC>50 µg/ml), P. dameselae subsp. Piscicida Sp 9587 (MIC=6.25 µg/ml), Salmonella typhimurium S1 (MIC>50 µg/ml), S. putrefaciens IAM 1509 (MIC=6.25 µg/ml), Vibrio anguillarum NCIBM 829 (MIC=12.5 µg/ml), Vibrio parahaemolyticus (MIC=25 µg/ml).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP02318 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP02318.
    • Formula

    • C79H117N17O15
    • Absent Amino Acids

    • ACDEHMNPQTVWY
    • Common Amino Acids

    • F
    • Mass

    • 1544.9
    • PI

    • 11
    • Basic Residues

    • 2
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 8
    • Net Charge

    • +2
    • Boman Index

    • 9.61
    • Hydrophobicity

    • 1.423
    • Aliphatic Index

    • 120
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 3

DRAMP02318

    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • Interaction of grammistins with lipids and their antibacterial activity.
    • Reference

    • Fish. Sci. 2001 Oct;67:928-933.
    • Author

    • Yokota H, Nagashima Y, Shiomi K.