• • DRAMP ID

  • DRAMP02344

• • Peptide Name

  • 40S ribosomal protein S30 (Fish, chordates, animals)

• • Source

  • Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)

• • Family

  • Belongs to the eukaryotic ribosomal protein eS30 family.

• • Gene

  • fau

• • Sequence

  • KVHGSLARAGK

• • Sequence Length

  • 11

• • UniProt Entry

  • P83328

• • Protein Existence

  • Protein level

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • [Ref.12147245] Gram-negetive bacteria: Escherichia coli (EC50>0.3 μM, MBC>0.3 μM), Listonella anguillarum (EC50>0.3 μM, MBC>0.3 μM) ;
    • Gram-positive bacteria: Bacillus subtilis (EC50=0.15–0.3 μM, MBC>0.3 μM), Planococcus citreus (EC50=0.02–0.04 μM, MBC=0.08 μM).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • No cytotoxicity information found in the reference(s) presented

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Linear

• • N-terminal Modification

  • Free

• • C-terminal Modification

  • Free

• • Nonterminal Modifications and Unusual Amino Acids

  • Free

• • Stereochemistry

  • L

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP02344.

DRAMP02344

• • Function

  • Antibacterial activity against Gram-positive bacteria and low activity against Gram-negative bacteria.

• ·Literature 1

• • Title

  • A novel antimicrobial function for a ribosomal peptide from rainbow trout skin.

• • Pubmed ID

  • 12147245

• • Reference

  • Biochem Biophys Res Commun. 2002 Aug 9;296(1):167-171.

• • Author

  • Fernandes JM, Smith VJ.