• • DRAMP ID

  • DRAMP02351

• • Peptide Name

  • NRC-10 (fish, chordates, animals)

• • Source

  • Pseudopleuronectes americanus (Winter flounder Z)

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • FFRLLFHGVHHVGKIKPRA

• • Sequence Length

  • 19

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Not found

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal

• • Target Organism

  • • Gram-negative bacteria: Aeromonas salmonicida 99-1 (MIC>64 µg/ml), Aeromonas salmonicida 97-4 (MIC=32 µg/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=16 µg/ml), Salmonella enterica serovar Typhimurium 14028s (MIC>64 µg/ml), Pseudomonas aeruginosa K799 (MIC=32 µg/ml), Pseudomonas aeruginosa Z61 (MIC=8 µg/ml), Escherichia coli CGSC 4908 (MIC=32 µg/ml), Escherichia coli UB1005 (MIC=32 µg/ml), Escherichia coli DC2 (MIC=32 µg/ml);
    • Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC=32 µg/ml), Staphylococcus aureus C623 (MRSA) (MIC=64 µg/ml).
    • Yeast: Candida albicans C627 (MIC>64 µg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP02351.

DRAMP02351

• • Comment

  • No comments found on DRAMP database

• ·Literature 1

• • Title

  • Novel antimicrobial peptides derived from flatfish genes.

• • Pubmed ID

  • 12878506

• • Reference

  • Antimicrob Agents Chemother. 2003 Aug;47(8):2464-2470.

• • Author

  • Patrzykat A, Gallant JW, Seo JK, Pytyck J, Douglas SE.