• • DRAMP ID

  • DRAMP02354

• • Peptide Name

  • Pleurocidin-like peptide WFY (fish, chordates, animals)

• • Source

  • Pseudopleuronectes americanus (Winter flounder) (Pleuronectes americanus)

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • FFRLLFHGVHHGGGYLNAA

• • Sequence Length

  • 19

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Not found

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-

• • Target Organism

  • • Gram-negative bacteria: Aeromonas salmonicida A449 field isolate (MIC>64 µg/ml), A. salmonicida 97-4 field isolate (MIC>64 µg/ml), Pseudomonas aeruginosa K799 (MIC>64 µg/ml), Pseudomonas aeruginosa Z61 (MIC=64 µg/ml), Escherichia coli CGSC4908 triple (MIC=64 µg/ml), Salmonella typhimurium 14028s (MIC>64 µg/ml), Salmonella typhimurium MS7953s (MIC=64 µg/ml);
    • Gram-positive bacteria: Staphylococcus epidermidis (human clinical isolates) (MIC>64 µg/ml), Staphylococcus aureus (MRSA) (MIC>64 µg/ml).
    • Fungi: Candida albica (MIC>64 µg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• Please click DRAMP02354_predicted_structure.pdb to download.

DRAMP02354

• • Comment

  • No comments found on DRAMP database

• ·Literature 1

• • Title

  • Identification, structure and differential expression of novel pleurocidins clustered on the genome of the winter flounder, Pseudopleuronectes americanus (Walbaum).

• • Pubmed ID

  • 12950255

• • Reference

  • Eur J Biochem. 2003 Sep;270(18):3720-3730.

• • Author

  • Douglas SE, Patrzykat A, Pytyck J, Gallant JW.