General Information

    • DRAMP ID

    • DRAMP02356

    • Peptide Name

    • HKPLP (pleurocidin-like peptide; glycine-rich; fish, chordates, animals)

    • Source

    • Hippocampus kuda Bleeker (Sea horse)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • FLGLIFHGLVHAGKLIHGLIHRNRG

    • Sequence Length

    • 25

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02356 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02356.

Physicochemical Information

    • Formula

    • C130H207N41O27

    • Absent Amino Acids

    • CDEMPQSTWY

    • Common Amino Acids

    • GL

    • Mass

    • 2776.33

    • PI

    • 12.01

    • Basic Residues

    • 7

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 12

    • Net Charge

    • +7

    • Boman Index

    • -4.8

    • Hydrophobicity

    • 0.516

    • Aliphatic Index

    • 140.4

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 6

DRAMP02356

DRAMP02356 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Identification, synthesis and characterization of a novel antimicrobial peptide HKPLP derived from Hippocampus kuda Bleeker.

    • Reference

    • J Antibiot (Tokyo). 2012 Mar;65(3):117-121.

    • Author

    • Sun D, Wu S, Jing C, Zhang N, Liang D, Xu A.