General Information
-
DRAMP ID
- DRAMP02375
-
Peptide Name
- Misgurin (weatherfish, chordates, animals)
-
Source
- Misgurnus anguillicaudatus (Oriental weatherfish) (Oriental weatherloach)
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Family
- Not found
-
Gene
- Not found
-
Sequence
- RQRVEELSKFSKKGAAARRRK
-
Sequence Length
- 21
-
UniProt Entry
- P81474
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Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Antifungal
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Target Organism
- B.subtilus, Staphylococcus aureus, Streptococcus mutans, Streptococcus pneumoniae, Pseudomonas putida, Escherichia coli, Salmonella typhimurium, Serratia spps, Candida albicans, Cryptococcus neoformans, Saccharomyces cerevisae.
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Alpha helix
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP02375.
Physicochemical Information
-
Formula
- C106H189N41O29
Absent Amino Acids
- CDHIMNPTWY
Common Amino Acids
- R
Mass
- 2501.92
PI
- 11.84
Basic Residues
- 9
Acidic Residues
- 2
Hydrophobic Residues
- 6
Net Charge
- +7
-
Boman Index
- -104.45
Hydrophobicity
- -1.638
Aliphatic Index
- 46.67
Half Life
-
- Mammalian:1 hour
- Yeast:2 min
- E.coli:2 min
Extinction Coefficient Cystines
- 0
Absorbance 280nm
- 0
Polar Residues
- 3
DRAMP02375
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
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Title
- A novel antimicrobial peptide from the loach, Misgurnus anguillicaudatus.
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Pubmed ID
- 9271200
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Reference
- FEBS Lett. 1997 Jul 14;411(2-3):173-178.
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Author
- Park CB, Lee JH, Park IY, Kim MS, Kim SC.