General Information

    • DRAMP ID

    • DRAMP02384

    • Peptide Name

    • Hepcidin AS-hepc2 (fish, chordates, animals)

    • Source

    • Acanthopagrus schlegelii (Black porgy)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • SPAGCRFCCGCCPNMRGCGVCCRF

    • Sequence Length

    • 24

    • Protein Existence

    • Predicted

Activity Information

    • Biological Activity

    • Not found

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02384 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02384.

Physicochemical Information

    • Formula

    • C98H156N34O27S9

    • Absent Amino Acids

    • DEHIKLQTWY

    • Common Amino Acids

    • C

    • Mass

    • 2531.07

    • PI

    • 8.53

    • Basic Residues

    • 3

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 4

    • Net Charge

    • +3

    • Boman Index

    • -26.64

    • Hydrophobicity

    • 0.454

    • Aliphatic Index

    • 16.25

    • Half Life

      • Mammalian:1.9 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 500

    • Absorbance 280nm

    • 21.74

    • Polar Residues

    • 14

DRAMP02384

DRAMP02384 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Molecular characterization of hepcidin AS-hepc2 and AS-hepc6 in black porgy (Acanthopagrus schlegelii): expression pattern responded to bacterial challenge and in vitro antimicrobial activity.

    • Reference

    • Comp Biochem Physiol B Biochem Mol Biol. 2011 Feb;158(2):155-163.

    • Author

    • Yang M, Chen B, Cai JJ, Peng H, Ling-Cai, Yuan JJ, Wang KJ.