• • DRAMP ID

  • DRAMP02398

• • Peptide Name

  • Antimicrobial peptide GP-19 (GP-19)

• • Source

  • Xenorhabdus budapestensis

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • GPVGLLSSPGSLPPVGGAP

• • Sequence Length

  • 19

• • UniProt Entry

  • B3A0L2

• • Protein Existence

  • Protein level

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal

• • Target Organism

  • • Gram-positive bacteria: Bacillus subtilis (IZ=19.04±0.2 mm), Bacillus megaterium (IZ=7.3±0.28 mm), Prototheca wickerhamii (IZ=10.3±0.33 mm);
    • Gram-negative bacteria: Xanthomonas campestris pv. vesicatoria (IZ=16.47±0.35 mm), Pseudomonas solanacearum (IZ=10.75±0.41 mm).
    • fungi: Phytophthora capsici (CD=16.62±1.07 mm), Verticillium dahlia (EC50=17.54 µg/ml), Fusarium graminearum (CD=12.04±0.87 mm), Fusarium omysporum (CD=21.64±0.4 mm).
    • NOTE: IZ = Inhibition Zone and CD = Colony diameter.

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP02398.

DRAMP02398

• • Function

  • GP-19 displays broad-spectrum antimicrobial activity against the tested bacteria and fungi.

• ·Literature 1

• • Title

  • Two novel antimicrobial peptides purified from the symbiotic bacteria Xenorhabdus budapestensis NMC-10.

• • Pubmed ID

  • 22497806

• • Reference

  • Peptides. 2012 Jun;35(2):253-260.

• • Author

  • Xiao Y, Meng F, Qiu D, Yang X.