General Information
-
DRAMP ID
- DRAMP02442
-
Peptide Name
- Ericin S (lantibiotic-like peptide)
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Source
- Bacillus subtilis A1/3 (Gram-positive bacteria)
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Family
- Not found
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Gene
- Not found
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Sequence
- WKSESVCTPGCVTGVLQTCFLQTITCNCHISK
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Sequence Length
- 32
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UniProt Entry
- No entry found
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Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial
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Target Organism
- B. amyloliquefaciens ATCC 15841, B. brevis ATCC 7577, B. cereus ATCC 14579, B. firmus ATCC 14575, B. polymyxa ATCC 842, B. sphaericus ATCC 14577, Bacillus subtilis natto DSM 1088, Bacillus subtilis DSM 3256, Bacillus subtilis DSM 3258, L. lactis IL-1403.
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Rich
-
Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP02442.
Physicochemical Information
-
Formula
- C149H240N40O46S5
Absent Amino Acids
- ADMRY
Common Amino Acids
- CT
Mass
- 3488.09
PI
- 7.83
Basic Residues
- 3
Acidic Residues
- 1
Hydrophobic Residues
- 9
Net Charge
- +2
-
Boman Index
- -17.95
Hydrophobicity
- 0.322
Aliphatic Index
- 75.94
Half Life
-
- Mammalian:2.8 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 5750
Absorbance 280nm
- 185.48
Polar Residues
- 16
DRAMP02442
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
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Title
- Two different lantibiotic-like peptides originate from the ericin gene cluster of Bacillus subtilis A1/3.
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Pubmed ID
- 11872722
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Reference
- J. Bacteriol. 2002; 184:1703-1711.
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Author
- Stein T, Borchert S, Conrad B, Feesche J, Hofemeister B, Hofemeister J, Entian KD.