General Information

    • DRAMP ID

    • DRAMP02443

    • Peptide Name

    • Ericin A (lantibiotic-like peptide)

    • Source

    • Bacillus subtilis A1/3 (Gram-positive bacteria)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • VLSKSLCTPGCITGPLQTCYLCFPTFAKC

    • Sequence Length

    • 29

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Rich

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02443 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02443.

Physicochemical Information

    • Formula

    • C138H220N32O38S5

    • Absent Amino Acids

    • DEHMNRW

    • Common Amino Acids

    • C

    • Mass

    • 3095.76

    • PI

    • 8.41

    • Basic Residues

    • 2

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 9

    • Net Charge

    • +2

    • Boman Index

    • 10.83

    • Hydrophobicity

    • 0.731

    • Aliphatic Index

    • 80.69

    • Half Life

      • Mammalian:100 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 1740

    • Absorbance 280nm

    • 62.14

    • Polar Residues

    • 14

DRAMP02443

DRAMP02443 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Two different lantibiotic-like peptides originate from the ericin gene cluster of Bacillus subtilis A1/3.

    • Reference

    • J. Bacteriol. 2002; 184:1703-1711.

    • Author

    • Stein T, Borchert S, Conrad B, Feesche J, Hofemeister B, Hofemeister J, Entian KD.