• DRAMP ID

    • DRAMP02474
    • Peptide Name

    • cathelicidin-BF15 (Snakes, reptiles, animals)
    • Source

    • Bungarus fasciatus (Banded krait)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • KFFRKLKKSVKKRAK
    • Sequence Length

    • 15
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
    • Target Organism

      • Gram-negative bacteria: Pseudomonas aeruginosa ATCC27853 (MIC=4.7 µg/ml), P. aeruginosa IS/DR (MIC=37.5 µg/ml), P. aeruginosa 08031205 IS/DR (MIC=18.7 µg/ml), P. aeruginosa 08031014 IS/DR (MIC=75 µg/ml), Escherichia coli ATCC25922 (MIC=18.7 µg/ml), E. coli 08A852 IS/DR (MIC=18.7 µg/ml), E. coli 08A866 IS/DR (MIC=18.7 µg/ml), E. coli 08031017 IS/DR (MIC=37.5 µg/ml), E. coli 08040722 IS/DR (MIC=9.4 µg/ml), K. pneumoniae 08040202 IS/DR (MIC=75 µg/ml), Salmonella Typhi IS/DR (MIC=1.2 µg/ml), Saccharibacillus kuerlensis (MIC=4.7 µg/ml).
      • Gram-positive bacteria: Bacillus subtilis (MIC=75 µg/ml), Staphylococcus aureus ATCC2592 (MIC=75 µg/ml), S. aureus 08A875 IS/DR (MIC=75 µg/ml), S. aureus 08031002 IS/DR (MIC>100 µg/ml).
      • Fungi: Candida albicans ATCC2002 (MIC=18.7 µg/ml).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP02474 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • Formula

    • C89H158N28O17
    • Absent Amino Acids

    • CDEGHIMNPQTWY
    • Common Amino Acids

    • K
    • Mass

    • 1892.41
    • PI

    • 12.05
    • Basic Residues

    • 9
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 5
    • Net Charge

    • +9
    • Boman Index

    • -55.36
    • Hydrophobicity

    • -1.447
    • Aliphatic Index

    • 52
    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 1

DRAMP02474

    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • Snake cathelicidin from Bungarus fasciatus is a potent peptide antibiotics.
    • Reference

    • PLoS One. 2008 Sep 16;3(9):e3217.
    • Author

    • Wang Y, Hong J, Liu X, Yang H, Liu R, Wu J, Wang A, Lin D, Lai R.