• • DRAMP ID

  • DRAMP02520

• • Peptide Name

  • OH-CATH (Snakes, reptiles, animals)

• • Source

  • Ophiophagus hannah (King cobra) (Naja hannah)

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • KRFKKFFKKLKNSVKKRAKKFFKKPRVIGVSIPF

• • Sequence Length

  • 34

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Not found

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram-

• • Target Organism

  • • Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=8 µg/ml), E. coli ML-35P (MIC=6 µg/ml), E. coli clinic strain (MIC=20 µg/ml), Pseudomonas aeruginosa ATCC 27853 (MIC=4 µg/ml), Pseudomonas aeruginosa PA 01 (MIC=2 µg/ml), Pseudomonas aeruginosa clinic strain (MIC=2 µg/ml), Enterobacter aerogenes clinic strain (MIC=2 µg/ml), E. cloacae clinic strain (MIC=1 µg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• Please click DRAMP02520_predicted_structure.pdb to download.

DRAMP02520

• • Comment

  • No comments found on DRAMP database

• ·Literature 1

• • Title

  • Identification and characterization of novel reptile cathelicidins from elapid snakes.

• • Pubmed ID

  • 18620012

• • Reference

  • Peptides. 2008 Oct;29(10):1685-1691.

• • Author

  • Zhao H, Gan TX, Liu XD, Jin Y, Lee WH, Shen JH, Zhang Y.