• DRAMP ID

    • DRAMP02520
    • Peptide Name

    • OH-CATH (Snakes, reptiles, animals)
    • Source

    • Ophiophagus hannah (King cobra) (Naja hannah)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • KRFKKFFKKLKNSVKKRAKKFFKKPRVIGVSIPF
    • Sequence Length

    • 34
    • UniProt Entry

    • No entry found
    • Protein Existence

    • Not found
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram-
    • Target Organism

      • Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=8 µg/ml), E. coli ML-35P (MIC=6 µg/ml), E. coli clinic strain (MIC=20 µg/ml), Pseudomonas aeruginosa ATCC 27853 (MIC=4 µg/ml), Pseudomonas aeruginosa PA 01 (MIC=2 µg/ml), Pseudomonas aeruginosa clinic strain (MIC=2 µg/ml), Enterobacter aerogenes clinic strain (MIC=2 µg/ml), E. cloacae clinic strain (MIC=1 µg/ml).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP02520 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP02520.
    • Formula

    • C202H334N56O38
    • Absent Amino Acids

    • CDEHMQTWY
    • Common Amino Acids

    • K
    • Mass

    • 4155.23
    • PI

    • 12.34
    • Basic Residues

    • 15
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 13
    • Net Charge

    • +15
    • Boman Index

    • -77.29
    • Hydrophobicity

    • -0.735
    • Aliphatic Index

    • 62.94
    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 4

DRAMP02520

DRAMP02520 chydropathy plot
    • Comment

    • No comments found on DRAMP database
  • ·Literature 1
    • Title

    • Identification and characterization of novel reptile cathelicidins from elapid snakes.
    • Reference

    • Peptides. 2008 Oct;29(10):1685-1691.
    • Author

    • Zhao H, Gan TX, Liu XD, Jin Y, Lee WH, Shen JH, Zhang Y.