• DRAMP ID

    • DRAMP02572
    • Peptide Name

    • Penaeidin-2b (Pen-2b; shrimps, Arthropods, animals)
    • Source

    • Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei)
    • Family

    • Belongs to the penaeidin family
    • Gene

    • Not found
    • Sequence

    • YRGGYTGPIPRPPPIGRPPLRPVCNACYRLSVSDARNCCIKFGSCCHLVK
    • Sequence Length

    • 50
    • Protein Existence

    • Homology
    • Biological Activity

    • Antimicrobial, Antibacterial, Antifungal
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Chitin-binding
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP02572 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP02572.
    • Formula

    • C240H384N74O62S6
    • Absent Amino Acids

    • EMQW
    • Common Amino Acids

    • P
    • Mass

    • 5490.51
    • PI

    • 9.55
    • Basic Residues

    • 9
    • Acidic Residues

    • 1
    • Hydrophobic Residues

    • 12
    • Net Charge

    • +8
    • Boman Index

    • -79.85
    • Hydrophobicity

    • -0.228
    • Aliphatic Index

    • 68.2
    • Half Life

      • Mammalian:2.8 hour
      • Yeast:10 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 4845
    • Absorbance 280nm

    • 98.88
    • Polar Residues

    • 20

DRAMP02572

DRAMP02572 chydropathy plot
    • Function

    • Antibacterial and antifungal activity. Presents chitin-binding activity.
    • Subcellular location

    • Cytoplasmic granule. Note
    • PTM

    • Contains three disulfide bonds 24-38; 27-45; 39-46 and lysine amide at K50.
  • ·Literature 1
    • Title

    • Diversity of the penaeidin antimicrobial peptides in two shrimp species.
    • Reference

    • Immunogenetics. 2002 Sep;54(6):442-445.
    • Author

    • Cuthbertson BJ, Shepard EF, Chapman RW, Gross PS.