General Information
-
DRAMP ID
- DRAMP02582
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Peptide Name
- Penaeidin-3i (Pen-3i; shrimps, Arthropods, animals)
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Source
- Litopenaeus vannamei (Whiteleg shrimp) (Penaeus vannamei)
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Family
- Belongs to the penaeidin family
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Gene
- Not found
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Sequence
- QVYKGGYTRPIPRPPPFVRPLPGGPIGPYNGRPVSCRGISFSQARSCCSRLGRCCHVGKGYS
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Sequence Length
- 62
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UniProt Entry
- Q963C5
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Protein Existence
- Homology
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Antifungal
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Chitin-binding
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
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Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP02582.
Physicochemical Information
-
Formula
- C294H463N93O77S5
Absent Amino Acids
- DEMW
Common Amino Acids
- GP
Mass
- 6692.79
PI
- 10.32
Basic Residues
- 11
Acidic Residues
- 0
Hydrophobic Residues
- 12
Net Charge
- +11
-
Boman Index
- -112.04
Hydrophobicity
- -0.49
Aliphatic Index
- 51.77
Half Life
-
- Mammalian:0.8 hour
- Yeast:10 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 6210
Absorbance 280nm
- 101.8
Polar Residues
- 27
DRAMP02582
Comments Information
Function
- Posesses antibacterial and antifungal activity. Presents chitin-binding activity.
Subcellular location
- Cytoplasmic granule. Note
PTM
- Contains two disulfide bonds 36-54; 48-55, Pyrrolidone carboxylic acid and Serine amide at position 1 and 62 respectively.
Literature Information
- ·Literature 1
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Title
- Diversity of the penaeidin antimicrobial peptides in two shrimp species.
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Pubmed ID
- 12242595
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Reference
- Immunogenetics. 2002 Sep;54(6):442-445.
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Author
- Cuthbertson BJ, Shepard EF, Chapman RW, Gross PS.