General Information

    • DRAMP ID

    • DRAMP02593

    • Peptide Name

    • Styelin-B (Styelin B; invertebrates, animals)

    • Source

    • Styela clava (Sea squirt)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GXFGPAFHSVSNFAKKHKTA

    • Sequence Length

    • 20

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02593 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02593.

Physicochemical Information

    • Formula

    • C94H137N27O23

    • Absent Amino Acids

    • CDEILMQRWY

    • Common Amino Acids

    • AFK

    • Mass

    • 2142.63

    • PI

    • 10.3

    • Basic Residues

    • 5

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 7

    • Net Charge

    • +5

    • Boman Index

    • -21.69

    • Hydrophobicity

    • -0.415

    • Aliphatic Index

    • 29.5

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 6

DRAMP02593

DRAMP02593 chydropathy plot

Comments Information

    • Function

    • Bactericidal against several Gram-positive and Gram-negative bacteria.

    • Tissue specificity

    • Hemocytes and pharyngeal tissues.

Literature Information

  • ·Literature 1

    • Title

    • Styelins, broad-spectrum antimicrobial peptides from the solitary tunicate, Styela clava.

    • Reference

    • Comp Biochem Physiol B Biochem Mol Biol. 1997 Nov;118(3):515-521.

    • Author

    • Lee IH, Cho Y, Lehrer RI.