• DRAMP ID

    • DRAMP02602
    • Peptide Name

    • Clavaspirin (chordates, animals)
    • Source

    • Styela clava (Sea squirt)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • FLRFIGSVIHGIGHLVHHIGVAL
    • Sequence Length

    • 23
    • Protein Existence

    • Transcript level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
    • Target Organism

    • [Swiss_Prot Entry O97395]Exhibits broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria
    • Hemolytic Activity

      • [Ref.12005415]has potent hemolytic activity
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Alpha helix
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP02602 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP02602.
    • Formula

    • C119H186N34O25
    • Absent Amino Acids

    • CDEKMNPQTWY
    • Common Amino Acids

    • GHI
    • Mass

    • 2493
    • PI

    • 9.78
    • Basic Residues

    • 5
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 13
    • Net Charge

    • +5
    • Boman Index

    • 21.13
    • Hydrophobicity

    • 1.291
    • Aliphatic Index

    • 160.87
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 5

DRAMP02602

DRAMP02602 chydropathy plot
    • Function

    • Has potent hemolytic activity.
  • ·Literature 1
    • Title

    • Clavaspirin, an antibacterial and haemolytic peptide from Styela clava.
    • Reference

    • J Pept Res. 2001 Dec;58(6):445-456.
    • Author

    • Lee IH, Zhao C, Nguyen T, Menzel L, Waring AJ, Sherman MA, Lehrer RI.