• • DRAMP ID

  • DRAMP02603

• • Peptide Name

  • Putative antimicrobial peptide A Northern Europe Heligoland (chordates, animals)

• • Source

  • Ciona intestinalis

• • Family

  • Not found

• • Gene

  • Not found

• • Sequence

  • AALRGALRAVARVGKAILPHVAIANPYVRTPYVHNNP

• • Sequence Length

  • 37

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Not found

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal

• • Target Organism

  • • Gram-positive bacteria: Bacillus megaterium (MIC=0.1 µM), Bacillus subtilis (MIC=3.1 µM), Staphylococcus aureus (MIC>25 µM), Staphylococcus epidermidis (MIC=25 µM).
    • Gram-negative bacteria: Escherichia coli K12 D31 (MIC=0.8 µM), Y. enterocolitica (MIC=3.1 µM), Klebsiella pneumoniae (MIC>25µM), Pseudomonas aeruginosa (MIC=12.5 µM), Serratia marcescens(MIC>25 µM).
    • Fungi: Candida albicans ATCC 10261 (MIC=6.3 µM), Candida albicans SC 5314 (MIC=6.3 µM).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP02603.

DRAMP02603

• • Comment

  • No comments found on DRAMP database

• ·Literature 1

• • Title

  • A reverse search for antimicrobial peptides in Ciona intestinalis: identification of a gene family expressed in hemocytes and evaluation of activity.

• • Pubmed ID

  • 17658598

• • Reference

  • Dev Comp Immunol. 2008;32(3):286-298.

• • Author

  • Fedders H, Leippe M.