• DRAMP ID

    • DRAMP02618
    • Peptide Name

    • Beta-defensin 118 (Defensin, beta 118; primates, mammals, animals)
    • Source

    • Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
    • Family

    • Belongs to the beta-defensin family
    • Gene

    • DEFB118
    • Sequence

    • AYGGEKKCWNRSGHCRKQCKDGEAVKETCKNHRACCVPSNEDH
    • Sequence Length

    • 43
    • Protein Existence

    • Homology
    • Biological Activity

    • Antimicrobial, Antibacterial
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Bridge
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP02618 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP02618.
    • Formula

    • C197H313N69O64S6
    • Absent Amino Acids

    • FILM
    • Common Amino Acids

    • CK
    • Mass

    • 4864.44
    • PI

    • 8.63
    • Basic Residues

    • 12
    • Acidic Residues

    • 6
    • Hydrophobic Residues

    • 6
    • Net Charge

    • +6
    • Boman Index

    • -144.41
    • Hydrophobicity

    • -1.405
    • Aliphatic Index

    • 20.47
    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 7365
    • Absorbance 280nm

    • 175.36
    • Polar Residues

    • 17

DRAMP02618

DRAMP02618 chydropathy plot
    • Function

    • Has antibacterial activity (Potential).
    • PTM

    • Contains three disulfide bonds (By similarity).
  • ·Literature 1
    • Title

    • Evolution and sequence variation of human beta-defensin genes.
    • Reference

    • Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases
    • Author

    • Hollox EJ, Armour JAL.