General Information
-
DRAMP ID
- DRAMP02621
-
Peptide Name
- Beta-defensin 132 (Defensin, beta 132; primates, mammals, animals)
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Source
- Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
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Family
- Belongs to the beta-defensin family
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Gene
- DEFB132
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Sequence
- GGSKCVSDTPGYCRTHCHRGETALFMCSPFRKCCISYSFLPQPDLPQLIGNHWPSRSRNTQRKNKKQQTTVTP
-
Sequence Length
- 73
-
UniProt Entry
- A4H265
-
Protein Existence
- Homology
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Bridge
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP02621.
Physicochemical Information
-
Formula
- C356H561N111O104S7
Absent Amino Acids
- ?
Common Amino Acids
- PSTCR
Mass
- 8284.47
PI
- 9.64
Basic Residues
- 14
Acidic Residues
- 3
Hydrophobic Residues
- 13
Net Charge
- +11
-
Boman Index
- -179.78
Hydrophobicity
- -0.851
Aliphatic Index
- 41.37
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 8855
Absorbance 280nm
- 122.99
Polar Residues
- 30
DRAMP02621
Comments Information
Function
- Has antibacterial activity (Potential).
PTM
- Contains three disulfide bonds (By similarity).
Literature Information
- ·Literature 1
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Title
- Evolution and sequence variation of human beta-defensin genes.
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Pubmed ID
- PubMed ID is not available
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Reference
- Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases
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Author
- Hollox EJ, Armour JAL.