General Information

    • DRAMP ID

    • DRAMP02656

    • Peptide Name

    • Alpha-defensin 2 (primates, mammals, animals)

    • Source

    • Macaca mulatta (Rhesus macaque)

    • Family

    • Not found

    • Gene

    • MNP2

    • Sequence

    • MRTLAILAAILLFALLAQAKSLQETADDAATQEQPGEDDQDLAVSFEENGLSTLRASGSQARRTCRCRFGRCFRRESYSGSCNINGRIFSLCCR

    • Sequence Length

    • 94

    • Protein Existence

    • Predicted

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02656 helical wheel diagram

    • Predicted Structure

    • There is no predicted structure for DRAMP02656.

Physicochemical Information

    • Formula

    • C436H711N137O141S7

    • Absent Amino Acids

    • HW

    • Common Amino Acids

    • ALR

    • Mass

    • 10352.69

    • PI

    • 7.56

    • Basic Residues

    • 12

    • Acidic Residues

    • 11

    • Hydrophobic Residues

    • 33

    • Net Charge

    • +1

    • Boman Index

    • -220.75

    • Hydrophobicity

    • -0.244

    • Aliphatic Index

    • 78.09

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 1865

    • Absorbance 280nm

    • 20.05

    • Polar Residues

    • 30

DRAMP02656

DRAMP02656 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • cDNA cloning of three alpha-defensins and three demidefensins from rhesus monkey bone marrow.

    • Reference

    • Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases

    • Author

    • Zhao C, Nguyen T, Lehrer RI.