• DRAMP ID

    • DRAMP02690
    • Peptide Name

    • Beta-defensin 119 (Defensin, beta 119; Beta-defensin 120; primates, mammals, animals)
    • Source

    • Pan troglodytes (Chimpanzee)
    • Family

    • Belongs to the beta-defensin family
    • Gene

    • DEFB119
    • Sequence

    • KRHILRRMGNSGICRASCKKNEQPYLYCRNYQSCCLQSYMRISISGKEENTDWSYEKQWPRLP
    • Sequence Length

    • 63
    • Protein Existence

    • Homology
    • Biological Activity

    • Antimicrobial, Antibacterial
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Bridge
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP02690 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP02690.
    • Formula

    • C327H515N101O95S7
    • Absent Amino Acids

    • FV
    • Common Amino Acids

    • RS
    • Mass

    • 7605.73
    • PI

    • 9.47
    • Basic Residues

    • 13
    • Acidic Residues

    • 5
    • Hydrophobic Residues

    • 11
    • Net Charge

    • +8
    • Boman Index

    • -188.85
    • Hydrophobicity

    • -1.095
    • Aliphatic Index

    • 51.11
    • Half Life

      • Mammalian:1.3 hour
      • Yeast:3 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 18700
    • Absorbance 280nm

    • 301.61
    • Polar Residues

    • 25

DRAMP02690

DRAMP02690 chydropathy plot
    • Function

    • Potentially has antibacterial activity.
    • PTM

    • Problely contains two disulfide bonds 14-28; 18-35.
  • ·Literature 1
    • Title

    • Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.
    • Reference

    • Physiol Genomics. 2005 Sep 21;23(1):5-17.
    • Author

    • Patil A.A, Cai Y, Sang Y, Blecha F, Zhang G.
  • ·Literature 2
    • Title

    • Evolution and sequence variation of human beta-defensin genes.
    • Reference

    • Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases
    • Author

    • Hollox EJ, Armour JAL.