General Information
-
DRAMP ID
- DRAMP02732
-
Peptide Name
- Beta-defensin 106A (Defensin, beta 106; Defensin, beta 106A; primates, mammals, animals)
-
Source
- Hylobates lar (Common gibbon) (White-handed gibbon)
-
Family
- Belongs to the beta-defensin family
-
Gene
- DEFB106A
-
Sequence
- FFDDKCDKLRGTCKNSCEKNEELTSFCQKSLKCCRTIQTCGNTTD
-
Sequence Length
- 45
-
UniProt Entry
- A4H213
-
Protein Existence
- Homology
Activity Information
-
Biological Activity
- Antimicrobial
-
Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP02732.
Physicochemical Information
-
Formula
- C210H342N62O74S7
Absent Amino Acids
- AHMPVWY
Common Amino Acids
- C
Mass
- 5143.82
PI
- 7.72
Basic Residues
- 8
Acidic Residues
- 7
Hydrophobic Residues
- 7
Net Charge
- +1
-
Boman Index
- -135.61
Hydrophobicity
- -0.889
Aliphatic Index
- 34.67
Half Life
-
- Mammalian:1.1 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 375
Absorbance 280nm
- 8.52
Polar Residues
- 21
DRAMP02732
Comments Information
Function
- Has antimicrobial activity (By similarity).
PTM
- Contains three disulfide bonds (By similarity).
Literature Information
- ·Literature 1
-
Title
- Evolution and sequence variation of human beta-defensin genes.
-
Pubmed ID
- PubMed ID is not available
-
Reference
- Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases
-
Author
- Hollox EJ, Armour JAL.