General Information
-
DRAMP ID
- DRAMP02734
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Peptide Name
- Beta-defensin 119 (Defensin, beta 119; Beta-defensin 120; primates, mammals, animals)
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Source
- Hylobates lar (Common gibbon) (White-handed gibbon)
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Family
- Belongs to the beta-defensin family
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Gene
- DEFB119
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Sequence
- KHHILRCMGNSGICRASCKKNEQPYLYCRNYQHCCLQSYMRISISGEEENTDWSYEKQWPRLP
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Sequence Length
- 63
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Protein Existence
- Homology
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Bridge
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Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP02734.
Physicochemical Information
-
Formula
- C326H500N98O96S8
Absent Amino Acids
- FV
Common Amino Acids
- CSERY
Mass
- 7584.64
PI
- 8.61
Basic Residues
- 12
Acidic Residues
- 6
Hydrophobic Residues
- 11
Net Charge
- +6
-
Boman Index
- -164.91
Hydrophobicity
- -0.995
Aliphatic Index
- 51.11
Half Life
-
- Mammalian:1.3 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 18825
Absorbance 280nm
- 303.63
Polar Residues
- 25
DRAMP02734
Comments Information
Function
- Potentially has antibacterial activity.
PTM
- Problely contains three disulfide bonds 7-34; 14-28; 18-35.
Literature Information
- ·Literature 1
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Title
- Evolution and sequence variation of human beta-defensin genes.
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Pubmed ID
- PubMed ID is not available
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Reference
- Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases
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Author
- Hollox EJ, Armour JAL.