General Information

    • DRAMP ID

    • DRAMP02749

    • Peptide Name

    • Dinoponeratoxin Da-3177 (ants, insects, animals)

    • Source

    • Dinoponera australis (Giant neotropical hunting ant)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • GLKDWWNKHKDKIIDVVKEMGKAGLQAA

    • Sequence Length

    • 28

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02749 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02749.

Physicochemical Information

    • Formula

    • C144H232N40O39S

    • Absent Amino Acids

    • CFPRSTY

    • Common Amino Acids

    • K

    • Mass

    • 3179.73

    • PI

    • 9.31

    • Basic Residues

    • 7

    • Acidic Residues

    • 4

    • Hydrophobic Residues

    • 11

    • Net Charge

    • +3

    • Boman Index

    • -40.09

    • Hydrophobicity

    • -0.654

    • Aliphatic Index

    • 87.14

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 11000

    • Absorbance 280nm

    • 407.41

    • Polar Residues

    • 4

DRAMP02749

DRAMP02749 chydropathy plot

Comments Information

    • Function

    • May have antibacterial activity, since it is predicted to form an amphipathic alpha helix.

    • Tissue specificity

    • Expressed by the venom gland.

Literature Information

  • ·Literature 1

    • Title

    • A biochemical characterization of the major peptides from the venom of the giant Neotropical hunting ant Dinoponera australis.

    • Reference

    • Toxicon. 2010 Apr 1;55(4):702-710.

    • Author

    • Johnson SR, Copello JA, Evans MS, Suarez AV.