General Information

    • DRAMP ID

    • DRAMP02750

    • Peptide Name

    • Defensin (ants, insects, animals)

    • Source

    • Formica aquilonia (Red wood ant)

    • Family

    • Belongs to the invertebrate defensin family (Type 1 subfamily)

    • Gene

    • Not found

    • Sequence

    • FTCDLLSGAGVDHSACAAHCILRGKTGGRCNSDRVCVCRA

    • Sequence Length

    • 40

    • Protein Existence

    • Homology

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Bridge

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02750 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02750.

Physicochemical Information

    • Formula

    • C166H276N58O53S6

    • Absent Amino Acids

    • EMPQWY

    • Common Amino Acids

    • C

    • Mass

    • 4124.73

    • PI

    • 8.36

    • Basic Residues

    • 7

    • Acidic Residues

    • 3

    • Hydrophobic Residues

    • 13

    • Net Charge

    • +4

    • Boman Index

    • -66.48

    • Hydrophobicity

    • 0.18

    • Aliphatic Index

    • 73.25

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 375

    • Absorbance 280nm

    • 9.62

    • Polar Residues

    • 17

DRAMP02750

DRAMP02750 chydropathy plot

Comments Information

    • Function

    • Antibacterial peptide mostly active against Gram-positive bacteria (By similarity).

Literature Information

  • ·Literature 1

    • Title

    • Identification and molecular characterization of defensin gene from the ant Formica aquilonia.

    • Reference

    • Insect Mol Biol. 2005 Aug;14(4):335-338.

    • Author

    • Viljakainen L, Pamilo P.