• DRAMP ID

    • DRAMP02803
    • Peptide Name

    • Mytilin-A (molluscas, animals)
    • Source

    • Mytilus edulis (Blue mussel)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • GCASRCKAKCAGRRCKGWASASFRGRCYCKCFRC
    • Sequence Length

    • 34
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
    • Target Organism

      • Gram-positive bacteria: Aerococcus viridans, Bacillus megaterium, Micrococcus luteus, Enterococcus faecalis, Staphylococcus aureus;
      • Gram-negative bacteria: Escherichia coli, Alteromonas carrageenovora, Pseudomonas alginovora, Cytophaga drobachiensis.
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP02803 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP02803.
    • Formula

    • C154H251N57O39S8
    • Absent Amino Acids

    • DEHILMNPQTV
    • Common Amino Acids

    • C
    • Mass

    • 3781.53
    • PI

    • 9.83
    • Basic Residues

    • 10
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 8
    • Net Charge

    • +10
    • Boman Index

    • -90.72
    • Hydrophobicity

    • -0.418
    • Aliphatic Index

    • 14.71
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 7490
    • Absorbance 280nm

    • 226.97
    • Polar Residues

    • 16

DRAMP02803

DRAMP02803 chydropathy plot
    • Function

    • Has antibacterial activity. It is active against the marine species Alteromonas carrageenovora, Pseudomonas alginovora and Cytophaga drobachiensis.
  • ·Literature 1
    • Title

    • Innate immunity. Isolation of several cysteine-rich antimicrobial peptides from the blood of a mollusc, Mytilus edulis.
    • Reference

    • J Biol Chem. 1996 Sep 6;271(36):21808-21813.
    • Author

    • Charlet M, Chernysh S, Philippe H, Hetru C, Hoffmann JA, Bulet P.