General Information

    • DRAMP ID

    • DRAMP02814

    • Peptide Name

    • Conolysin-Mt2

    • Source

    • Conus mustelinus (Weasel cone)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • FHPSLWVLIPQYIQLIRKILKS

    • Sequence Length

    • 22

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antibacterial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02814 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02814.

Physicochemical Information

    • Formula

    • C132H210N32O28

    • Absent Amino Acids

    • ACDEGMNT

    • Common Amino Acids

    • IL

    • Mass

    • 2693.32

    • PI

    • 10.29

    • Basic Residues

    • 4

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 11

    • Net Charge

    • +4

    • Boman Index

    • 0.01

    • Hydrophobicity

    • 0.486

    • Aliphatic Index

    • 155

    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 6990

    • Absorbance 280nm

    • 332.86

    • Polar Residues

    • 3

DRAMP02814

DRAMP02814 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Conolysin-Mt: a conus peptide that disrupts cellular membranes.

    • Reference

    • Biochemistry. 2007 Nov 6;46(44):12586-12593.

    • Author

    • Biggs J.S, Rosenfeld Y, Shai Y, Olivera B.M.