General Information

    • DRAMP ID

    • DRAMP02826

    • Peptide Name

    • Isracidin

    • Source

    • Bos taurus (Bovine)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • RPKHPIKHQGLPQEVLNENLLRF

    • Sequence Length

    • 23

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP02826 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP02826.

Physicochemical Information

    • Formula

    • C125H203N39O32

    • Absent Amino Acids

    • ACDMSTWY

    • Common Amino Acids

    • L

    • Mass

    • 2764.23

    • PI

    • 9.99

    • Basic Residues

    • 6

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 7

    • Net Charge

    • +4

    • Boman Index

    • -55.68

    • Hydrophobicity

    • -0.987

    • Aliphatic Index

    • 97.39

    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 3

DRAMP02826

DRAMP02826 chydropathy plot

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Antimicrobial activity of two peptides casecidin 15 and 17, found naturally in bovine colostrum.

    • Reference

    • J Appl Microbiol. 2009 Jan;106(1):233-240.

    • Author

    • Birkemo GA, O'Sullivan O, Ross RP, Hill C.