• • DRAMP ID

  • DRAMP02835

• • Peptide Name

  • Enkelytin (one chain of Proenkephalin-A; mammals, animals)

• • Source

  • Bos taurus (Bovine)

• • Family

  • Belongs to the opioid neuropeptide precursor family

• • Gene

  • PENK

• • Sequence

  • FAEPLPSEEEGESYSKEVPEMEKRYGGFM

• • Sequence Length

  • 29

• • UniProt Entry

  • P01211,Q2T9T4

• • Protein Existence

  • Protein level

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram+

• • Target Organism

  • • Gram-positive bacteria: Micrococcus luteus (MIC=0.2-0.4 µM), Bacillus megaterium (MIC=0.2-0.4 µM).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Not found

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP02835.

DRAMP02835

• • Comment

  • No comments found on DRAMP database

• ·Literature 1

• • Title

  • Partial characterization of the mRNA that codes for enkephalins in bovine adrenal medulla and human pheochromocytoma.

• • Pubmed ID

  • 6952189

• • Reference

  • Proc Natl Acad Sci U S A. 1982 Jan;79(2):360-364.

• • Author

  • Comb M, Herbert E, Crea R.

• ·Literature 2

• • Title

  • The C-terminal bisphosphorylated proenkephalin-A-(209-237)-peptide from adrenal medullary chromaffin granules possesses antibacterial activity.

• • Pubmed ID

  • 8654396

• • Reference

  • Eur J Biochem. 1996 Feb 1;235(3):516-525.

• • Author

  • Goumon Y, Strub JM, Moniatte M, Nullans G, Poteur L, Hubert P, Van Dorsselaer A, Aunis D, Metz-Boutigue MH.